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[单相团注CT尿路造影——减少儿童肾脏和尿路先天性异常诊断中辐射剂量的新方法]

[One-phase split-bolus CT Urography - a novel approach to reduce radiation dose in diagnostics of congenital anomalies of kidneys and urinary tract in children].

作者信息

Bombiński Przemysław, Brzewski Michał, Warchoł Stanisław, Gołębiowski Marek

机构信息

Department of Pediatric Radiology, Medical University of Warsaw, Warsaw, Poland.

Department of Pediatric Surgery and Urology, Medical University of Warsaw, Warsaw, Poland.

出版信息

Dev Period Med. 2017;21(4):402-407. doi: 10.34763/devperiodmed.20172104.402407.

Abstract

BACKGROUND

Low-dose CT Urography (LD-CTU) has become a standard procedure in urinary tract abnormalities in children, especially when MR Urography is not available. Standard one-phase CTU is performed in excretory phase. There is also a split-bolus technique, which combines two or even three phases during one scan and provides more clinical information without higher radiation exposure. It can be implemented for congenital anomalies of kidneys and urinary tract (CAKUT) in children, however, this application is not deeply discussed in scientific literature. Aim of this publication is to present the protocol and determine the role of LD-CTU in diagnostic imaging of CAKUT in children.

MATERIAL AND METHODS

Close to 300 CTUs in children were performed as a standard of care during the last 6 years in our Department. Diagnostic accuracy in suspected CAKUT was analyzed, depending on applied protocol − standard excretory CTU, multiphase CTU and two different one-phase split-bolus CTU protocols.

RESULTS

Visualization of the urinary tract was adequate in all study protocols. However, more clinically significant information was received in vascular-excretory protocol, including vascular and renal anatomy. Radiation exposure was similar or even lower than in other study protocols.

CONCLUSIONS

One-phase split-bolus CTU protocol is a novel approach in low-dose diagnostic imaging of CAKUT in children. Combination of vascular and excretory phases has been shown as very effective technique, especially in comprehensive anatomical assessment of the abnormality and qualification to surgical intervention.

摘要

背景

低剂量CT尿路造影(LD-CTU)已成为儿童尿路异常的标准检查方法,尤其是在无法进行磁共振尿路造影时。标准的单相CT尿路造影在排泄期进行。还有一种团注分割技术,在一次扫描中结合两个甚至三个阶段,在不增加辐射暴露的情况下提供更多临床信息。它可用于儿童先天性肾脏和尿路畸形(CAKUT),然而,这一应用在科学文献中并未得到深入讨论。本出版物的目的是介绍该方案并确定LD-CTU在儿童CAKUT诊断成像中的作用。

材料与方法

在过去6年中,我们科室对近300例儿童进行了CT尿路造影,作为标准治疗手段。根据应用的方案——标准排泄期CT尿路造影、多期CT尿路造影和两种不同的单相团注分割CT尿路造影方案,分析疑似CAKUT的诊断准确性。

结果

在所有研究方案中,尿路的显影都足够。然而,在血管-排泄期方案中获得了更多具有临床意义的信息,包括血管和肾脏解剖结构。辐射暴露与其他研究方案相似甚至更低。

结论

单相团注分割CT尿路造影方案是儿童CAKUT低剂量诊断成像的一种新方法。血管期和排泄期的结合已被证明是一种非常有效的技术,尤其是在对异常进行全面解剖评估和确定手术干预方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d042/8522927/67e871e4a89a/jmotherandchild-21-402-g001.jpg

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