基于 BODIPY 功能化磁性纳米粒子的高灵敏和选择性的荧光和比色传感器用于检测活细胞中的铅。
A highly sensitive and selective turn-on fluorogenic and chromogenic sensor based on BODIPY-functionalized magnetic nanoparticles for detecting lead in living cells.
机构信息
Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Jinju 660-701, Korea.
出版信息
Chemistry. 2010 Oct 11;16(38):11549-53. doi: 10.1002/chem.201001772. Epub 2010 Aug 27.
PMID:20803587
Abstract
A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe(3)O(4)@SiO(2) core/shell nanoparticles 1 has been prepared. Chemosensor 1 exhibits a high affinity and selectivity for Pb(2+) over competing metal ions tested. Moreover, confocal microscopy, and flow cytometry experiments established that 1 can be used for detecting Pb(2+) levels within living cell.
摘要
一种基于 BODIPY 功能化 Fe(3)O(4)@SiO(2)核/壳纳米粒子 1 的新型氟荧光化学传感器已经被制备出来。化学传感器 1 对 Pb(2+)具有高亲和力和选择性，优于测试的竞争金属离子。此外，共聚焦显微镜和流式细胞术实验表明 1 可用于检测活细胞内的 Pb(2+)水平。
Zotero 插件