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一种基于硼二吡咯功能化磁性二氧化硅纳米粒子的选择性氟离子载体:从人血中去除Pb2+

A selective fluoroionophore based on BODIPY-functionalized magnetic silica nanoparticles: removal of Pb2+ from human blood.

作者信息

Lee Hye Young, Bae Doo Ri, Park Ji Chan, Song Hyunjoon, Han Won Seok, Jung Jong Hwa

机构信息

Department of Chemistry and Research Institute of Natural Sciences and Environmental Biotechnology National Core Research Center, Gyeongsang National University, Jinju 660-701, Korea.

出版信息

Angew Chem Int Ed Engl. 2009;48(7):1239-43. doi: 10.1002/anie.200804714.

Abstract

Get the lead out: The title fluorescence receptor exhibits a high affinity and selectivity for Pb(2+) over competing metal ions in water (see picture) with an overall emission change of approximately 8-fold at the emission maximum for Pb(2+). The fluorescence receptor can remove 96 % of 100 ppb Pb(2+) from human blood, and can be useful and effective for the selective and rapid removal of Pb(2+) in vivo.

摘要

去除铅

该标题荧光受体对水中的Pb(2+)表现出高于竞争性金属离子的高亲和力和选择性(见图),在Pb(2+)的发射最大值处总体发射变化约为8倍。该荧光受体可以从人体血液中去除96%的100 ppb Pb(2+),并且对于体内选择性快速去除Pb(2+)可能是有用且有效的。

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