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[1例重症肌无力合并胸腺瘤扩大胸腺切除术后辅助放疗后发生放射性肺炎及双侧张力性气胸的病例]

[A case of radiation-related pneumonia and bilateral tension pneumothorax after extended thymectomy and adjuvant radiation for thymoma with myasthenia gravis].

作者信息

Nakasone Etsuko, Nakayama Masayuki, Bando Masashi, Endo Shunsuke, Hironaka Mitsugu, Sugiyama Yukihiko

机构信息

Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University.

出版信息

Nihon Kokyuki Gakkai Zasshi. 2010 Aug;48(8):584-8.

Abstract

A 62-year-old man was admitted to our hospital with a 2-month history of progressive cough and dyspnea. He had undergone thymectomy for thymoma with myasthenia gravis. Adjuvant radiation of 50 Gy had been performed until 6 months before the symptoms developed. Chest computed tomography showed infiltrative findings even outside the irradiated area. We diagnosed radiation-related pneumonia, and 30 mg per day prednisolone was initiated. On the final day, he developed bilateral tension pneumothorax. After chest tube drainage, the right S5 bulla was resected with video-assisted thoracoscopic surgery (VATS). The right pneumothorax caused the bilateral tension pneumothorax, because the right and left thoracic cavity communicated in the anterior mediastinum after thymectomy. We should be aware of the risk of bilateral tension pneumothorax following radiation-related pneumonia after extended thymectomy and adjuvant radiation in patients with myasthenia gravis.

摘要

一名62岁男性因进行性咳嗽和呼吸困难2个月入住我院。他曾因胸腺瘤合并重症肌无力接受过胸腺切除术。在症状出现前6个月,已进行了50 Gy的辅助放疗。胸部计算机断层扫描显示即使在照射区域外也有浸润性表现。我们诊断为放射性肺炎,并开始使用每天30 mg泼尼松龙治疗。在最后一天,他出现了双侧张力性气胸。胸腔闭式引流后,通过电视辅助胸腔镜手术(VATS)切除了右肺下叶S5段肺大疱。右侧气胸导致双侧张力性气胸,因为胸腺切除术后左右胸腔在前纵隔相通。我们应该意识到,重症肌无力患者在扩大胸腺切除术后接受辅助放疗后发生放射性肺炎时,有双侧张力性气胸的风险。

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