Bhardwaj Himanshu, Bhardwaj Bhaskar, Youness Houssein A
Department of Pulmonary Medicine and Critical Care, Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Lung India. 2013 Oct;30(4):360-2. doi: 10.4103/0970-2113.120624.
Spontaneous pneumothorax (SPTX) is a potentially devastating rare complication of the thoracic radiation therapy. Most of the cases in the medical literature, have been described in lymphoma patients receiving radiation therapy. The pathogenesis of this adverse event remains undefined although different mechanisms have been proposed. We present a case of post-radiation therapy SPTX in a non-small cell lung cancer (NSCLC), following intensity modulated radiation therapy (IMRT), which to our knowledge is the first such reported case related to this newer mode of radiation therapy. This report highlights the importance of keeping a close eye for this complication as timely treatment with chest tube insertion and drainage of the pneumothorax can be a lifesaving in these patients.
自发性气胸(SPTX)是胸部放射治疗一种潜在的严重罕见并发症。医学文献中的大多数病例是在接受放射治疗的淋巴瘤患者中描述的。尽管已经提出了不同的机制,但这种不良事件的发病机制仍不明确。我们报告一例非小细胞肺癌(NSCLC)患者在接受调强放射治疗(IMRT)后发生放射治疗后SPTX的病例,据我们所知,这是首例与这种新型放射治疗模式相关的此类报道病例。本报告强调了密切关注这种并发症的重要性,因为及时插入胸管并引流气胸对这些患者可能是救命的。