School of Food and Nutritional Sciences, University College Cork, Republic of Ireland.
Public Health Nutr. 2011 Mar;14(3):551-6. doi: 10.1017/S1368980010002417. Epub 2010 Aug 31.
European governments have yet to introduce mandatory folic acid fortification of foods for neural tube defect prevention because of uncertainty about the long-term safety of high intake of folic acid. Novel folate-enriched eggs have been proposed as offering a practical way of increasing intake of natural folates, which do not have the same safety concerns as synthetic folic acid. Our objective was to estimate the potential increase in folate supply that could occur in European Union (EU) countries if normal eggs were replaced by folate-enriched eggs.
FAOSTAT data on daily per capita availability of eggs were linked to mean folate concentrations of un-enriched and folate-enriched eggs from three representative feeding trials from the recent literature.
Data were collated in Microsoft Excel.
The study used food balance sheets for Europe for 1961-2003 and for twenty-six individual EU countries for 2003.
There has been little variation in egg supply in Europe over the past 40 years, with eggs providing only about 1·3-1·6 % of total energy. In 2003, the average per capita egg supply across twenty-six EU countries was 32·8 g/d, equivalent to a little over half an egg. Even if the folate concentrations of all eggs across the EU were increased two- to threefold, per capita folate supply would increase only by about 25 μg/d.
At current enrichment levels, the availability of novel folate-enriched eggs will have little impact on folate supply in EU countries. In the absence of mandatory fortification, additional natural folate sources are needed urgently.
由于不确定高剂量叶酸摄入的长期安全性,欧洲各国政府尚未强制要求在食品中添加叶酸以预防神经管缺陷。新型叶酸强化鸡蛋被提议为一种增加天然叶酸摄入量的实用方法,天然叶酸不会像合成叶酸那样存在安全问题。我们的目的是估计如果用叶酸强化鸡蛋代替普通鸡蛋,欧盟国家的叶酸供应量可能会增加多少。
将 FAOSTAT 关于鸡蛋每日人均供应量的数据与最近文献中三个代表性喂养试验的未强化和强化叶酸鸡蛋的平均叶酸浓度相关联。
数据在 Microsoft Excel 中汇总。
该研究使用了欧洲 1961-2003 年的食物平衡表和 2003 年 26 个欧盟国家的个别数据。
在过去的 40 年中,欧洲的鸡蛋供应变化不大,鸡蛋只提供了约 1.3-1.6%的总能量。2003 年,26 个欧盟国家的人均鸡蛋供应量为 32.8 克/天,相当于一个半鸡蛋多一点。即使欧盟所有鸡蛋的叶酸浓度增加两到三倍,人均叶酸供应量也只会增加约 25μg/天。
在当前的强化水平下,新型叶酸强化鸡蛋的供应将对欧盟国家的叶酸供应影响不大。在没有强制强化的情况下,迫切需要其他天然叶酸来源。