Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON.
Can J Public Health. 2009 Jul-Aug;100(4):281-4. doi: 10.1007/BF03403947.
In 1998, the Canadian government mandated folic acid fortification of white flour and enriched grain products to lower the prevalence of neural tube defects. There is now growing concern over the potential harmful effects of too much folic acid on some segments of the population. Given that the actual amount of folate in Canadian foods is unknown, the objective of this study was to measure the folate content in selected fortified foods.
Using data from the 2001 Food Expenditure Survey and the ACNielsen Company, 95 of the most commonly purchased folic acid-fortified foods in Canada were identified. Folate concentrations in these foods were determined using tri-enzyme digestion followed by microbiological assay. Analyzed values were compared to those in the Canadian Nutrient File (2007b, CNF) and to label values.
The analyzed folate content of foods was, on average, 151% +/- 63 of the CNF values. Analyzed values as a percent of CNF values ranged from 116% in the "rolls and buns" category to 188% in "ready-to-eat cereals". Analyzed values were higher than label values for "breads", "rolls and buns" and "ready-to-eat cereals" (141%, 118% and 237%, respectively [p < 0.05]).
Ten years after folic acid fortification of the food supply, neither the CNF nor label values accurately reflect actual amounts of folate in foods. Further, overage differences by food category hinder the development of future strategies designed to strike the right balance between health benefits and risks; monitoring of fortified foods for their nutrient content is required.
1998 年,加拿大政府规定在白面粉和强化谷物产品中添加叶酸,以降低神经管缺陷的发生率。现在人们越来越担心过多的叶酸对某些人群可能产生有害影响。鉴于加拿大食品中叶酸的实际含量未知,本研究旨在测量选定强化食品中的叶酸含量。
利用 2001 年食品支出调查和 ACNielsen 公司的数据,确定了加拿大最常购买的 95 种叶酸强化食品。使用三酶消化法和微生物测定法测定这些食品中的叶酸浓度。分析值与加拿大营养文件(2007b,CNF)和标签值进行比较。
食品中分析的叶酸含量平均为 CNF 值的 151% +/- 63。分析值与 CNF 值的百分比范围从“卷饼和小圆面包”类别的 116%到“即食谷物”类别的 188%。“面包”、“卷饼和小圆面包”和“即食谷物”的分析值高于标签值(分别为 141%、118%和 237%[p < 0.05])。
在食品供应中添加叶酸 10 年后,CNF 或标签值都不能准确反映食品中叶酸的实际含量。此外,按食品类别划分的差异会阻碍制定未来在健康益处和风险之间取得平衡的战略;需要对强化食品的营养成分进行监测。