Ministry of Health, PO Box 1176, Jerusalem 91010, Israel.
J Public Health Policy. 2010 Sep;31(3):318-23. doi: 10.1057/jphp.2010.22.
When four deaths occurred in one week among influenza vaccine recipients, the Israeli Health Ministry suspended its 2006 influenza vaccination campaign pending investigation of the causes of death. Medical histories of the deceased vaccinees, quality control reports, and laboratory test results were examined. Prior vaccine use that season and a risk assessment of the vaccinated population were also considered. All four decedents had been treated for cardiac and other chronic diseases, and none had experienced post-injection symptoms suggesting adverse reaction to influenza vaccine. Quality control and laboratory reports confirmed vaccine batch safety, and no adverse effects had been reported among any other vaccine recipients. Investigators found no causal connection between the deaths and the vaccine, and the Health Ministry resumed the campaign. Israeli public health officials viewed the investigation as vital to maintaining broad confidence in the public health system, and in future vaccination campaigns.
当一周内有四起流感疫苗接种者死亡事件发生时,以色列卫生部暂停了其 2006 年的流感疫苗接种运动,以等待对死亡原因的调查。对死者的医疗史、质量控制报告和实验室检测结果进行了检查。还考虑了该季节之前的疫苗使用情况和接种人群的风险评估。所有四名死者都曾接受过心脏和其他慢性疾病的治疗,且均未出现注射后症状表明对流感疫苗有不良反应。质量控制和实验室报告证实了疫苗批次的安全性,且在任何其他疫苗接种者中均未报告任何不良反应。调查人员未发现死亡与疫苗之间存在因果关系,卫生部恢复了接种运动。以色列公共卫生官员认为,这项调查对于维护公众对公共卫生系统的广泛信心,以及未来的疫苗接种运动至关重要。