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不同传感器参数对整块晶体正电子发射断层扫描(PET)探测器空间分辨率性能的影响。

Impact on the Spatial Resolution Performance of a Monolithic Crystal PET Detector Due to Different Sensor Parameters.

作者信息

Li Xiaoli, Lockhart Cate, Lewellen Tom K, Miyaoka Robert S

机构信息

University of Washington Department of Physics, Seattle, WA USA (phone: 206-543-0629; fax: 206-543-8356).

出版信息

IEEE Nucl Sci Symp Conf Rec (1997). 2009 Oct 24;2009:3102-3105. doi: 10.1109/NSSMIC.2009.5401674.

Abstract

The performance characteristics of a monolithic crystal PET detector utilizing a novel sensor on the entrance surface (SES) design is reported. To facilitate this design, we propose to utilize a 2D silicon photomultiplier (SiPM) array device. SiPMs are a form of Geiger-Muller mode avalanche photodiodes (GMAPD) that can provide signal gain similar to a photomultiplier tube (PMT). Since these devices are still under active development, their performance parameters are changing. Using a multi-step simulation process, we investigated how different SiPM parameters affect the performance of a monolithic crystal PET detector. These parameters include gain variability between different channels; gain instability; and dark count noise. The detector simulated was a 49.6 mm by 49.6 mm by 15 mm LYSO crystal detector readout by a 16 by 16 array of 2.8 mm by 2.8 mm SiPM elements. To reduce the number of signal channels that need to be collected, the detector utilizes row-column summing. A statistics based positioning method is used for event positioning and depth of interaction (DOI) decoding. Of the variables investigated, the dark count noise had the largest impact on the intrinsic spatial resolution. Gain differences of 5-10% between detector calibration and detector testing had a modest impact on the intrinsic spatial resolution performance and led to a slight bias in positioning. There was no measurable difference with a gain variability of up to 25% between the individual SiPM channels. Based upon these results we are planning to cool our detectors below room temperature to reduce dark count noise and to actively control the temperature of the SiPMs to reduce drifts in gain over time.

摘要

报告了一种在入射表面(SES)设计上采用新型传感器的整体式晶体正电子发射断层扫描(PET)探测器的性能特征。为便于这种设计,我们提议使用二维硅光电倍增管(SiPM)阵列器件。SiPM是盖革 - 米勒模式雪崩光电二极管(GMAPD)的一种形式,可提供与光电倍增管(PMT)类似的信号增益。由于这些器件仍在积极研发中,其性能参数不断变化。通过多步模拟过程,我们研究了不同的SiPM参数如何影响整体式晶体PET探测器的性能。这些参数包括不同通道之间的增益变化性、增益不稳定性以及暗计数噪声。所模拟的探测器是一个尺寸为49.6毫米×49.6毫米×15毫米的LYSO晶体探测器,由一个16×16阵列的2.8毫米×2.8毫米SiPM元件读出。为减少需要采集的信号通道数量,探测器采用行列求和。基于统计的定位方法用于事件定位和相互作用深度(DOI)解码。在所研究的变量中,暗计数噪声对固有空间分辨率的影响最大。探测器校准和探测器测试之间5 - 10%的增益差异对固有空间分辨率性能有适度影响,并导致定位出现轻微偏差。单个SiPM通道之间增益变化性高达25%时,没有可测量的差异。基于这些结果,我们计划将探测器冷却至室温以下以降低暗计数噪声,并积极控制SiPM的温度以减少增益随时间的漂移。

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本文引用的文献

1
Measured Temperature Dependence of Scintillation Camera Signals Read Out by Geiger-Müller Mode Avalanche Photodiodes.
IEEE Nucl Sci Symp Conf Rec (1997). 2009 Oct 24;2009:2662-2665. doi: 10.1109/NSSMIC.2009.5401995.
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Depth of interaction decoding of a continuous crystal detector module.
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