Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
J Clin Rheumatol. 2010 Sep;16(6):287-9. doi: 10.1097/RHU.0b013e3181eeebfb.
We report a patient who had Graves disease and recently developed subcutaneous nodules over both lower limbs. Initially, gouty tophi were suspected by the endocrinologist so he was referred to the rheumatology clinic. However, a series of studies, including soft tissue ultrasonography, magnetic resonance image, and biopsy revealed nodular mucinosis resulting from Graves dermopathy. Nodular mucinosis is an unusual form of myxedema which mimics tophaceous gout, and should be considered in patients with Graves disease presenting with subcutaneous nodules.
我们报告了一例 Graves 病患者,近期于双下肢出现皮下结节。起初,内分泌医生怀疑为痛风性痛风石,因此将其转至风湿科就诊。然而,一系列检查,包括软组织超声、磁共振成像和活检,结果显示为 Graves 眼病所致结节性黏液水肿。结节性黏液水肿是黏液水肿的一种罕见形式,类似于痛风石性痛风,在 Graves 病患者出现皮下结节时应考虑该病。