Wriston Cooper C, Rubin Adam I, Martin Linda K, Kossard Steven, Murrell Dedee F
Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Am J Dermatopathol. 2012 Jun;34(4):e50-4. doi: 10.1097/DAD.0b013e3181f87e91.
Midline mucinosis was observed in a 14-year-old man, which was confined to the midline of the back and appeared as asymptomatic, nonindurated, hyperpigmented plaques. Skin biopsies showed prominent interstitial mucinosis with perivascular lymphocytic infiltration. A literature review of plaque-like mucinosis revealed 14 previous cases with this distinct presentation that may overlap with reticular erythematous mucinosis and connective tissue disease. Midline mucinosis has been previously reported in prepubertal children but is rare.
一名14岁男性被观察到患有中线黏液病，病变局限于背部中线，表现为无症状、非硬结性、色素沉着斑。皮肤活检显示明显的间质黏液病伴血管周围淋巴细胞浸润。对斑块状黏液病的文献回顾发现，之前有14例具有这种独特表现的病例，可能与网状红斑性黏液病和结缔组织病重叠。中线黏液病此前在青春期前儿童中有报道，但较为罕见。
