Fang Wei, Zhang Jian, He Zuo-Xiang
Department of Nuclear Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Nucl Med Commun. 2010 Nov;31(11):981-4. doi: 10.1097/MNM.0b013e32833f393f.
Dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and systolic dysfunction with normal ventricular wall thickness. More recent studies have shown that the coronary microcirculation may be directly affected in cardiomyopathies. Left ventricular regional myocardial perfusion, wall motion, and metabolism abnormalities are often present in patients with DCM. These data support the possibility that myocardial ischemia may play an important role in the development of DCM and have important prognostic value in patients with DCM. We need to pay attention to the assessment of myocardial blood flow and myocardial ischemia in patients with DCM. Furthermore, anti-ischemic therapy may improve left ventricular function and clinical outcomes in patients with heart failure resulted from DCM.
扩张型心肌病（DCM）的特征是心室腔扩大和收缩功能障碍，而心室壁厚度正常。最近的研究表明，心肌病可能直接影响冠状动脉微循环。DCM患者常出现左心室局部心肌灌注、壁运动和代谢异常。这些数据支持心肌缺血可能在DCM的发生发展中起重要作用，并且对DCM患者具有重要预后价值的可能性。我们需要关注DCM患者的心肌血流和心肌缺血评估。此外，抗缺血治疗可能改善因DCM导致心力衰竭患者的左心室功能和临床结局。
