Division of Geriatric Research, Institute of Population Health Sciences, National Health Research Institutes, No 35, Keyan Road, Zhunan Town, Miaoli County 350, Taiwan.
Arch Gerontol Geriatr. 2011 Sep-Oct;53(2):e118-24. doi: 10.1016/j.archger.2010.07.006. Epub 2010 Sep 1.
This longitudinal study was conducted between 1994 and 2004 in a cohort of Southern Taiwan community-living elderly residents. The study aims to explore the trajectories of depression and how these patterns differed between respondents who survived and those who died during data collection phases; this study also investigated how health status change and health/social service use predicted the different trajectories of depression. Eight hundred and ten participants had completed all six waves of the survey or were followed-up at each wave until death in the prospective study in Kaohsiung City. Depressive symptoms were evaluated by the Short Psychiatric Evaluation Schedule (SPES). Changes in levels of depression during the ageing process were identified. Different trajectories clearly reflected heterogeneity within depression and the association with mortality. The study highlighted that diabetes, gastrointestinal problems, heart disease and disability, whether at baseline or as new occurrences, were predictors of health decline. High uses of health/social services were also predictive of increased depression. These findings identified depression as a highly dynamic process, characterized by different trajectories of depression between states of no, mild and severe depression. Greater awareness of these various trajectories should potentially improve the prevention and/or management strategies of depression.
本纵向研究于 1994 年至 2004 年在台湾南部社区居住的老年居民队列中进行。本研究旨在探讨抑郁的轨迹,以及这些模式在数据收集阶段存活和死亡的受访者之间有何不同;本研究还调查了健康状况的变化以及健康/社会服务的使用如何预测抑郁的不同轨迹。在高雄市的前瞻性研究中,810 名参与者完成了所有六轮调查或在每一轮随访至死亡。使用短期精神评估量表 (SPES) 评估抑郁症状。确定了在衰老过程中抑郁水平的变化。不同的轨迹清楚地反映了抑郁的异质性以及与死亡率的关联。研究强调,糖尿病、胃肠道问题、心脏病和残疾,无论是在基线还是新出现,都是健康状况下降的预测因素。高频率使用健康/社会服务也预示着抑郁程度的增加。这些发现表明抑郁是一个高度动态的过程,其特征是无抑郁、轻度抑郁和重度抑郁状态之间的抑郁轨迹不同。对这些不同轨迹的更多认识,有可能改善抑郁的预防和/或管理策略。