Han Sujeong, Lee Jun-Young, Cho Sung-Il, Oh Dae Jong, Yoon Dae Hyun
Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.
Psychiatry Investig. 2023 Apr;20(4):293-300. doi: 10.30773/pi.2022.0188. Epub 2023 Mar 31.
The aims of our study were to identify distinct trajectories of cognitive function using the group-based trajectory model. We also investigate which demographic factors act as risk factors for cognitive decline in each group.
The data from the Seoul National University Hospital Healthcare System Gangnam Center, from 2005 to 2019. The number of study subjects was 637. We used a group-based model to identify cognitive function trajectories. Multinomial logistic regression was employed to define risk factors for cognitive function decline.
The cognitive function trajectories among adults over 40 years of age were heterogeneous. We identified four trajectories: high (27.3%), medium (41.0%), low (22.7%), and rapid decline (9.1%). Older age, male, low educational level, bad dietary habits, diabetes mellitus, technical worker, and lower income increased the likelihood of a cognitive function decline.
A younger age, a higher educational level, professional worker, good dietary habits, no diabetes mellitus, and no obesity improved cognitive function. A combination of these factors can improve "cognitive reserve" and delay cognitive decline. Interventions to prevent cognitive decline are needed after identification of high-risk groups for cognitive decline.
我们研究的目的是使用基于群体的轨迹模型来识别认知功能的不同轨迹。我们还调查了哪些人口统计学因素在每组中作为认知衰退的风险因素。
数据来自首尔国立大学医院医疗系统江南中心，时间跨度为2005年至2019年。研究对象有637人。我们使用基于群体的模型来识别认知功能轨迹。采用多项逻辑回归来确定认知功能衰退的风险因素。
40岁以上成年人的认知功能轨迹是异质性的。我们识别出四种轨迹：高（27.3%）、中（41.0%）、低（22.7%）和快速衰退（9.1%）。年龄较大、男性、教育水平低、饮食习惯差、糖尿病、技术工人和收入较低会增加认知功能衰退的可能性。
较年轻的年龄、较高的教育水平、专业工作者、良好的饮食习惯、无糖尿病和无肥胖可改善认知功能。这些因素的组合可以改善“认知储备”并延缓认知衰退。在识别出认知衰退的高危人群后，需要采取干预措施来预防认知衰退。
