Department of Clinical Epidemiology and Biostatistics, McMaster University, DTC-314, 1280 Main Street West, Hamilton, ON, Canada, L8S 4L8.
Age Ageing. 2010 Nov;39(6):738-45. doi: 10.1093/ageing/afq105. Epub 2010 Sep 1.
to investigate the population impact on functional disability of chronic conditions individually and in combination.
data from 9,008 community-dwelling individuals aged 65 and older from the Canadian Study of Health and Aging (CSHA) were used to estimate the population attributable risk (PAR) for chronic conditions after adjusting for confounding variables. Functional disability was measured using activity of daily living (ADL) and instrumental activity of daily living (IADL).
five chronic conditions (foot problems, arthritis, cognitive impairment, heart problems and vision) made the largest contribution to ADL- and IADL-related functional disabilities. There was variation in magnitude and ranking of population attributable risk (PAR) by age, sex and definition of disability. All chronic conditions taken simultaneously accounted for about 66% of the ADL-related disability and almost 50% of the IADL-related disability.
in community-dwelling older adults, foot problems, arthritis, cognitive impairment, heart problems and vision were the major determinants of disability. Attempts to reduce disability burden in older Canadians should target these chronic conditions; however, preventive interventions will be most efficient if they recognize the differences in the drivers of PAR by sex, age group and type of functional disability being targeted.
分别和联合研究慢性疾病对功能障碍的人群影响。
本研究使用了来自加拿大老龄化健康研究(CSHA)的 9008 名 65 岁及以上的社区居住者的数据,在调整混杂变量后,估计了慢性疾病的人群归因风险(PAR)。功能障碍使用日常生活活动(ADL)和工具性日常生活活动(IADL)来衡量。
五种慢性疾病(足部问题、关节炎、认知障碍、心脏问题和视力问题)对 ADL 和 IADL 相关功能障碍的影响最大。人群归因风险(PAR)的大小和排名因年龄、性别和残疾定义而有所不同。同时考虑所有慢性疾病,大约 66%的 ADL 相关残疾和近 50%的 IADL 相关残疾归因于这些疾病。
在社区居住的老年人中,足部问题、关节炎、认知障碍、心脏问题和视力是残疾的主要决定因素。为了减轻加拿大老年人的残疾负担,应该针对这些慢性疾病进行干预;然而,如果预防干预措施能够认识到性别、年龄组和目标功能障碍类型对 PAR 的驱动因素的差异,那么它们将更有效。