Mohaptra Sudhaldev, Jha C B
Department of Rasa Shastra, Faculty of Ayurveda, Institution of Medical Sciences, Banaras Hindu University, India.
Int J Ayurveda Res. 2010 Apr;1(2):82-6. doi: 10.4103/0974-7788.64409.
Swarna makshika [SM], a mineral having various therapeutic uses, has been used since long in Ayurveda. The present study was conducted to generate a fingerprint for raw and processed SM using techniques which can be used by pharmacies. Powdered SM was heated in an iron pan by adding lemon juice for 3 days, till liberation of sulfur fumes stopped. Bhasma of this shuddha SM was obtained by triturating it withit with shuddha gandhaka and lemon juice. It was then subjected to heat in 09* putas, and for firing in each puta, 4 kg cow dung cakes were used. To assure the quality of bhasma, rasa shastra quality control tests like nischandratva, varitara, amla pariksha, etc., were used. After the bhasma complied with these tests, the bhasma was analyzed using X-ray Diffraction (XRD) analysis of raw SM and SM bhasma revealed that raw SM contains CuFeS(2), and SM bhasma contains Fe(2)O(3), FeS(2), CuS and SiO(2). Scanning Electron Microscope (SEM) studies showed that the grains in SM bhasma were uniformly arranged in agglomerates of size 1-2 microns as compared to the raw SM which showed a scattered arrangement of grains of size 6-8 microns. It may be concluded that raw SM is a complex compound which gets converted into a mixture of simple compounds having very small particle size after the particular process of marana. This is the first report of fingerprinting of SM bhasma prepared using this particular method.
斯瓦纳马克希卡[SM]是一种具有多种治疗用途的矿物质，在阿育吠陀医学中已被长期使用。本研究旨在利用药房可用的技术为生的和加工后的SM生成指纹图谱。将SM粉末加入柠檬汁后在铁锅中加热3天，直至硫磺烟雾释放停止。将这种纯净的SM与纯净的硫磺和柠檬汁研磨，得到其药粉。然后在9个煅烧锅中加热，每个煅烧锅使用4千克牛粪饼进行煅烧。为确保药粉质量，采用了如纯净度、变化度、酸度检测等吠陀医学质量控制测试。药粉通过这些测试后，对生的SM和SM药粉进行X射线衍射（XRD）分析，结果显示生的SM含有CuFeS₂，而SM药粉含有Fe₂O₃、FeS₂、CuS和SiO₂。扫描电子显微镜（SEM）研究表明，与显示6 - 8微米大小颗粒分散排列的生的SM相比，SM药粉中的颗粒以1 - 2微米大小的团聚体均匀排列。可以得出结论，生的SM是一种复杂化合物，经过特定的煅烧过程后转化为具有非常小粒径的简单化合物混合物。这是使用这种特定方法制备的SM药粉指纹图谱的首次报告。
