Multi-Disciplinary Centre for Biomedical research, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be university), Kirumampakkam, Puducherry, 607403, India.
Biol Trace Elem Res. 2021 Jun;199(6):2145-2148. doi: 10.1007/s12011-020-02353-y. Epub 2020 Aug 27.
Swarna bindu prashana (SBP) is a metallic medicinal preparation widely used in Ayurveda pediatrics. The main ingredients of SBP are swarna prashan (gold nanoparticle), gou ghrita (cow ghee), madhu (honey), and other medhya dravyas (drugs which enhance intellectual, memory). According to the Indian classical text, SBP has been proposed as a potent medicine for immunotherapies and vaccine development due to its indefinite size, shapes, charges, and surface functionality. In this review, we describe the plausible mechanism of SBP in dendritic cells maturation and subsequent T cell activation. But being herbo-metallic preparation, its safety and efficacy are well supported by the classical publications of Ayurveda. To conclude, SBP is an immune booster for infants against any viral disease, and it is necessary to validate its safety and efficacy through systematic methodological research.
梵丹补(SBP)是一种在阿育吠陀儿科学中广泛使用的金属药用制剂。SBP 的主要成分是梵丹补(金纳米颗粒)、牛酥(酥油)、蜂蜜和其他提神药(增强智力、记忆力的药物)。根据印度古典文献,由于 SBP 具有不定的大小、形状、电荷和表面功能,因此被提议作为免疫疗法和疫苗开发的有效药物。在这篇综述中,我们描述了 SBP 在树突状细胞成熟和随后 T 细胞激活中的可能机制。但是,作为一种草本金属制剂,它的安全性和有效性在阿育吠陀的经典文献中得到了很好的支持。总之,SBP 是婴儿对抗任何病毒性疾病的免疫增强剂,有必要通过系统的方法学研究来验证其安全性和有效性。