Graduate School of Pharmaceutical Sciences, University of Tokushima, 1-78 Shomachi, Tokushima 770-8505, Japan.
J Nat Med. 2011 Jan;65(1):217-23. doi: 10.1007/s11418-010-0462-1. Epub 2010 Sep 3.
Seven new dammarane-type triterpenoids, including two 20(S)-hydroxy-25-methoxy-dammar-23-enes (1 and 2), two 20(S),24(R)-epoxydammaranes (3 and 4), a cabralealactone (5), and two 20(S),25-epoxydammaranes (6 and 7), together with seven known triterpenes (8-14), were isolated from the floral spikes of Betula platyphylla var. japonica. The structures for all compounds were elucidated by the analyses of extensive spectroscopic data, as well as chemical examinations.
从华西桦的花序中分离得到了 7 种新的达玛烷型三萜,包括 2 种 20(S)-羟基-25-甲氧基达玛-23-烯(1 和 2)、2 种 20(S),24(R)-环氧达玛烷(3 和 4)、1 种卡瓦内酯(5)和 2 种 20(S),25-环氧达玛烷(6 和 7),以及 7 种已知的三萜(8-14)。通过广泛的光谱数据分析以及化学鉴定,确定了所有化合物的结构。