连翘干燥果实中的达玛烷型衍生物。

Dammarane derivatives from the dried fruits of Forsythia suspensa.

作者信息

Rouf A S, Ozaki Y, Rashid M A, Rui J

机构信息

Department of Pharmacy, University of Dhaka, Bangladesh.

出版信息

Phytochemistry. 2001 Apr;56(8):815-8. doi: 10.1016/s0031-9422(01)00028-0.

DOI:10.1016/s0031-9422(01)00028-0

PMID:11324910

Abstract

Anti-inflammatory activity guided fractionation of the n-hexane soluble fraction of a 70% aqueous methanolic extract of the dried fruits of Forsythia suspensa afforded two new triterpenes. The structures of these compounds were elucidated as 3beta-acetyl-20,25-epoxydammarane-24alpha-ol (1) and 3beta-acetyl-20,25-epoxydammarane-24beta-ol (2) on the basis of spectral data interpretation as well as by comparison with those of structurally similar compounds.

摘要

抗炎活性导向的连翘干燥果实70%甲醇水溶液提取物正己烷可溶部分的分离得到了两种新的三萜类化合物。基于光谱数据解释以及与结构相似化合物的比较，这些化合物的结构被鉴定为3β-乙酰基-20,25-环氧达玛烷-24α-醇（1）和3β-乙酰基-20,25-环氧达玛烷-24β-醇（2）。