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HIV的垂直传播——最新进展

Vertical transmission of HIV-an update.

作者信息

Lala Mamatha M, Merchant Rashid H

机构信息

CCDT/MSF/Wadia Group of Hospitals, Kalina, Santacruz (East), Mumbai, 400098, Maharashtra, India.

出版信息

Indian J Pediatr. 2010 Nov;77(11):1270-6. doi: 10.1007/s12098-010-0184-0. Epub 2010 Sep 3.

Abstract

One of the greatest successes in AIDS research to date has by far been the discovery of successful interventions that interrupt the transmission of HIV from mother to child. It is however important to note that these successes have occurred largely in countries with great resources and the least burden of perinatal transmission of HIV. In the developing world wherein currently 95% of vertical transmission of HIV occurs, it is highly condemnable that still every minute an infected infant is said to be born in spite of the fact that vertical transmission is largely preventable, mainly because translating knowledge into practice is not always possible or feasible; This has led to a continuous growing numbers of children with HIV, thereby making pediatric HIV a looming problem rapidly draining the already burdened health care system of these countries. It is the need of the hour to appropriately address the challenges to achieve zero percent transmission of HIV from an infected mother to her child thereby giving a hope for an AIDS-free new generation worldwide.

摘要

迄今为止,艾滋病研究最重大的成功之一,当属发现了能阻断艾滋病毒母婴传播的有效干预措施。然而,必须指出的是,这些成功大多出现在资源丰富、围产期艾滋病毒传播负担最轻的国家。在目前95%的艾滋病毒垂直传播发生的发展中世界,尽管事实上垂直传播在很大程度上是可以预防的,但仍据说每分钟就有一名感染婴儿出生,这是非常应受谴责的;这导致感染艾滋病毒的儿童数量持续增加,从而使儿科艾滋病毒成为一个迫在眉睫的问题,迅速耗尽这些国家本已负担沉重的医疗保健系统。当务之急是妥善应对各种挑战,以实现感染艾滋病毒的母亲将病毒零传播给孩子,从而为全球无艾滋病的新一代带来希望。

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