Crozet N
Institut National de la Recherche Agronomique, Unité Biologie de la Fécondation, Jouy-en-Josas/France.
Eur J Cell Biol. 1990 Dec;53(2):326-32.
The proximal centriole of the sperm was incorporated into the oocyte, at fertilization and a small aster of microtubules formed in the neck region containing the centriole. At late pronuclear stage, the sperm astral microtubules were located in the narrow cytoplasmic space between the apposed pronuclei. One or two centrioles were observed in/or close to the sperm neck region lying between the apposed pronuclei. Short microtubules radiated from the pericentriolar material which surrounded the centrioles. These results indicate that the proximal centriole of the sperm is not lost after incorporation into the ooplasm, as it is usually thought for mammals, but persists through the first cell cycle of the zygote. Moreover, the centriole inherited from the sperm reproduces at the pronuclear stage and migrates to one pole of the first mitotic spindle.
受精时，精子的近端中心粒进入卵母细胞，并在包含中心粒的颈部区域形成一个小的微管星体。在原核晚期，精子星体微管位于相对原核之间狭窄的细胞质空间中。在相对原核之间的精子颈部区域内或附近观察到一两个中心粒。短微管从围绕中心粒的中心粒周围物质放射状发出。这些结果表明，精子的近端中心粒在进入卵质后并未如通常认为的哺乳动物那样丢失，而是在合子的第一个细胞周期中持续存在。此外，从精子继承的中心粒在原核阶段进行复制，并迁移到第一个有丝分裂纺锤体的一极。
