Dow Division of Urologic Health Services Research, Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Urol Oncol. 2010 Sep-Oct;28(5):546-9. doi: 10.1016/j.urolonc.2009.12.022.
In an attempt to reduce morbidity, focal targeted therapies and active surveillance have become increasingly popular treatment choices for localized prostate cancer. However, these modalities rely heavily on accurate and reliable tumor localization information provided by a prostate biopsy. Evidence that our contemporary biopsy techniques can do little more than detect some prostate cancers is notably lacking. What is meant by the accuracy and reliability of a prostate biopsy and why they are such important concepts to focal therapy and active surveillance are discussed.
为了降低发病率，局部前列腺癌的靶向治疗和主动监测已成为越来越受欢迎的治疗选择。然而，这些方法严重依赖于前列腺活检提供的准确可靠的肿瘤定位信息。目前明显缺乏证据表明我们的当代活检技术能够发现更多的前列腺癌。本文讨论了前列腺活检的准确性和可靠性的含义，以及它们对靶向治疗和主动监测如此重要的原因。
