Villéga Frédéric, Picard Fabienne, Espil-Taris Caroline, Husson Marie, Michel Véronique, Pedespan Jean-Michel
Department of Child Neurology, University Hospital of Bordeaux, 33076 Bordeaux Cedex, France.
Brain Dev. 2011 Jun;33(6):525-9. doi: 10.1016/j.braindev.2010.08.008. Epub 2010 Sep 2.
Benign nocturnal alternating hemiplegia (BNAH) of childhood is distinct from the classic form of malignant alternating hemiplegia of childhood [1]. It is characterized by hemiplegic attacks occurring exclusively during sleep [2]. It can be misdiagnosed as migraine, nocturnal frontal lobe epilepsy, benign rolandic epilepsy, Panayiotopoulos syndrome, or sleep-related movement disorder [1-4]. Only nine patients have been described to date, with typically, a normal development [1,5-7]. In order to insist about the benignity of the affection, we report two cases: a new three-year-old boy suffering from BNAH and a patient already published to show positive evolution at fourteen years of age. BNAH is a rare disorder but may be underdiagnosed. Making an early diagnosis can help to describe to the parents the good prognosis without treatment.
儿童良性夜间交替性偏瘫（BNAH）与儿童恶性交替性偏瘫的经典形式不同[1]。其特征是偏瘫发作仅在睡眠期间出现[2]。它可能被误诊为偏头痛、夜间额叶癫痫、良性罗兰多癫痫、帕纳约托普洛斯综合征或睡眠相关运动障碍[1-4]。迄今为止，仅报道了9例患者，通常发育正常[1,5-7]。为了强调该疾病的良性性质，我们报告两例病例：一名新诊断的3岁患BNAH的男孩以及一名已发表病例的患者，该患者14岁时病情呈积极进展。BNAH是一种罕见疾病，但可能存在诊断不足的情况。早期诊断有助于向家长说明无需治疗预后良好。
