Rizk B, Morcos S, Avery S, Elder K, Brinsden P, Mason B, Edwards R
Bourn-Hallam Medical Centre, London, UK.
Hum Reprod. 1990 Nov;5(8):1025-8. doi: 10.1093/oxfordjournals.humrep.a137211.
Between 1985 and 1989, one unilateral twin and four bilateral tubal pregnancies were encountered among 124 extrauterine pregnancies and 1648 intrauterine pregnancies following in-vitro fertilization and embryo transfer. The two factors associated with this high incidence of single and multiple extrauterine pregnancies were tubal damage and multiple embryo transfer. Embryos at different stages of development appear to have the capacity to implant ectopically. Despite advances in diagnostic capabilities, ectopic pregnancy remains a major cause of maternal mortality. Early diagnosis prior to rupture must be made if mortality and morbidity are to be abolished. The use of transvaginal sonography has improved the diagnosis of ectopic pregnancy and should be routinely used in all pregnancies following assisted conception. The identification of an intrauterine pregnancy should not be sufficient to rule out the possibility of an extrauterine pregnancy or even bilateral tubal pregnancies.
在1985年至1989年间，在124例体外受精和胚胎移植后的宫外孕以及1648例宫内孕中，出现了1例单侧双胎和4例双侧输卵管妊娠。与单胎和多胎宫外孕高发生率相关的两个因素是输卵管损伤和多胚胎移植。处于不同发育阶段的胚胎似乎都有异位着床的能力。尽管诊断能力有所进步，但宫外孕仍然是孕产妇死亡的主要原因。若要消除死亡率和发病率，必须在破裂前进行早期诊断。经阴道超声检查的应用改善了宫外孕的诊断，应在所有辅助受孕后的妊娠中常规使用。确定宫内妊娠并不足以排除宫外孕甚至双侧输卵管妊娠的可能性。
