冷干空气激发联合声鼻反射测量术用于检测非特异性鼻高反应性。

Use of cold dry air provocation with acoustic rhinometry in detecting nonspecific nasal hyperreactivity.

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Inha University School of Medicine, Incheon, Korea.

出版信息

Am J Rhinol Allergy. 2010 Jul-Aug;24(4):260-2. doi: 10.2500/ajra.2010.24.3488.

DOI:10.2500/ajra.2010.24.3488

PMID:20819462

Abstract

BACKGROUND

Cold dry air provocation is useful for evaluating nonspecific nasal hyperreactivity. However, there is no research on nasal volume and dimensions after cold dry air provocation. In this respect, acoustic rhinometry is a useful tool in objectively assessing nasal cavity volume and dimension. The goal of this study was to evaluate nonspecific hyperreactivity using cold dry air provocation with acoustic rhinometry.

METHODS

Cold dry air provocation with acoustic rhinometry was performed on 21 healthy volunteers (group A), 24 patients with allergic rhinitis (group B), and 32 patients with nonallergic rhinitis (group C). The change in symptoms using a visual analog scale (VAS), amount of rhinorrhea, and change of total nasal volume (TNV) and minimal cross-sectional area (MCA) were measured in all three groups.

RESULTS

The two patient groups showed greater change in nasal symptoms (VAS, 2.0 +/- 2.3 in group C versus 0.9 +/- 1.8 in group A), more rhinorrhea (0.4 +/- 0.7 g in group B and 0.3 +/- 0.3 g in group C versus 0.1 +/- 0.1 g in group A), and greater change in total nasal volume (TNV) and MCA. The patient group with history of nonspecific hyperreactivity showed more rhinorrhea (0.5 +/- 0.7 g versus 0.1 +/- 0.2 g) and greater change in TNV and MCA (TNV, 56.8 +/- 39.5% versus 18.0 +/- 17.0%; MCA, 86.6 +/- 81.0% versus 11.5 +/- 9.7%).

CONCLUSION

Cold dry air provocation with acoustic rhinometry could be a useful adjunct tool for detecting nonspecific hyperreactivity.

摘要

背景

冷干空气激发对于评估非特异性鼻高反应性很有用。然而，目前还没有关于冷干空气激发后鼻腔容积和尺寸的研究。在这方面，鼻声反射测量术是客观评估鼻腔容积和尺寸的有用工具。本研究的目的是使用鼻声反射测量术评估冷干空气激发后的非特异性高反应性。

方法

对 21 名健康志愿者（A 组）、24 名过敏性鼻炎患者（B 组）和 32 名非过敏性鼻炎患者（C 组）进行冷干空气激发和鼻声反射测量术。在所有三组中，使用视觉模拟量表（VAS）测量症状变化、鼻涕量以及总鼻容积（TNV）和最小横截面积（MCA）的变化。

结果

两组患者组的鼻部症状变化更大（VAS，C 组为 2.0 +/- 2.3，A 组为 0.9 +/- 1.8），鼻涕量更多（B 组为 0.4 +/- 0.7 g，C 组为 0.3 +/- 0.3 g，A 组为 0.1 +/- 0.1 g），TNV 和 MCA 变化更大。有非特异性高反应性病史的患者组的鼻涕量更多（0.5 +/- 0.7 g 与 0.1 +/- 0.2 g），TNV 和 MCA 的变化更大（TNV，56.8 +/- 39.5% 与 18.0 +/- 17.0%；MCA，86.6 +/- 81.0% 与 11.5 +/- 9.7%）。