Laboratory of Microsystems, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH 1015 Lausanne, Switzerland.
Lab Chip. 2010 Oct 21;10(20):2771-7. doi: 10.1039/c004988c. Epub 2010 Sep 6.
Controlling alginate gel formation by diffusion of Ca(2+) ions through a filter barrier, a layer-by-layer deposition technique with resolution on the size scale of a single cell is presented. It offers the possibility of exposing cells under biocompatible conditions to microheterogeneous three-dimensional environments, mimicking the layered structure of extracellular matrix in tissues.
通过扩散钙离子通过过滤屏障控制藻酸盐凝胶形成，提出了一种具有单细胞尺寸分辨率的层层沉积技术。它为在生物相容条件下使细胞暴露于微异质三维环境提供了可能性，模拟了组织中细胞外基质的分层结构。
