Department of Surgery, South Auckland Clinical School, Middlemore Hospital, University of Auckland, Auckland, New Zealand.
Obes Surg. 2010 Nov;20(11):1484-90. doi: 10.1007/s11695-010-0267-z.
This is the largest single-centre series of single-stage laparoscopic sleeve gastrectomy (LSG) reporting on perioperative outcomes, weight loss, comorbidity resolution including urological outcomes and results in the super obese. Review of prospectively collected data for patients who underwent LSG from March 2007-August 2009.
There were 253 patients with a mean age of 44 years (SD, 9) and a mean preoperative body mass index (BMI) of 50 kg/m(2) (SD, 7). There were 17 (7%) major complications and no deaths. The mean follow-up was 9 months. One hundred and seventy-one patients with a mean follow-up of 12 months had a mean postoperative weight loss of 41 kg (SD, 16) and mean excess BMI (meBMI) loss of 59% (SD, 22).
One hundred fourteen patients were super obese (BMI, >50 kg/m(2)). The mean weight loss was 45 kg (SD, 18), and the meBMI lost was 49% (SD, 21). Super-obese patients experienced more complications (p = 0.02) and lost less eBMI (49% vs. 61%; p < 0.01). Fifty-three patients (46%) remained morbidly obese (BMI, >40 kg/m(2)) postoperatively. Hypertension and diabetes improved or resolved in 73 (79%) and 73 (90%) patients, respectively. Stress urinary incontinence was reported preoperatively in 60 (32%) females, and complete resolution or improvement was reported in 54 (90%) patients.
LSG provides satisfactory weight loss and resolution of comorbidities in the short- and medium-term with inferior, though acceptable, results in the super obese.
这是最大的单中心系列之一,报道了单阶段腹腔镜袖状胃切除术(LSG)的围手术期结果、减重效果、合并症缓解情况,包括泌尿系统结果和超级肥胖患者的结果。回顾 2007 年 3 月至 2009 年 8 月期间接受 LSG 的患者的前瞻性收集数据。
共有 253 例患者,平均年龄为 44 岁(标准差,9 岁),术前平均体重指数(BMI)为 50kg/m²(标准差,7kg/m²)。有 17 例(7%)发生重大并发症,无死亡。平均随访时间为 9 个月。171 例患者平均随访 12 个月,术后体重减轻 41kg(标准差,16kg),平均多余 BMI(meBMI)减轻 59%(标准差,22%)。
114 例患者为超级肥胖(BMI>50kg/m²)。平均体重减轻 45kg(标准差,18kg),meBMI 减轻 49%(标准差,21%)。超级肥胖患者并发症更多(p=0.02),meBMI 减少较少(49% vs. 61%;p<0.01)。53 例(46%)患者术后仍为病态肥胖(BMI>40kg/m²)。73 例(79%)高血压和 73 例(90%)糖尿病患者得到改善或缓解。60 例(32%)女性术前有压力性尿失禁,54 例(90%)患者完全缓解或改善。
LSG 在短期和中期内提供了令人满意的体重减轻和合并症缓解效果,而在超级肥胖患者中则效果稍差,但可接受。