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腹腔镜袖状胃切除术治疗超肥胖患者:6 至 8 年后随访 93%,体重减轻 48%。

Laparoscopic sleeve gastrectomy for super obese patients: forty-eight percent excess weight loss after 6 to 8 years with 93% follow-up.

机构信息

Department of Veterans Affairs, Pittsburgh Healthcare System, University Drive, Pittsburgh, PA, USA.

出版信息

Ann Surg. 2012 Aug;256(2):262-5. doi: 10.1097/SLA.0b013e31825fe905.

Abstract

OBJECTIVES

In this study, we report long-term outcomes of high-risk, high-BMI (body mass index) patients who underwent laparoscopic sleeve gastrectomy (LSG).

BACKGROUND

Short- and medium-term data appear to support the effectiveness of LSG, but long-term data to support its durability are sparse.

METHODS

A prospective database was reviewed on all high-risk patients who underwent LSG as part of a staged approach for surgical treatment of severe obesity between January 2002 and February 2004. We included only patients who did not proceed to second-stage surgery (gastric bypass). Analyzed data included demographics, BMI, comorbidities, and surgical outcomes. All partial gastrectomies were performed using a 50F bougie.

RESULTS

Seventy-four patients underwent LSG, and follow-up data were available on 69 of 74 patients (93%). The mean age was 50 years (25-78) and the mean number of co-morbidities was 9.6. Perioperative mortality (<30 days) was zero, and the incidence of short- and long-term postoperative complications was 15%. The mean overall follow-up time period was 73 months (38-95). Mean excess weight loss (EWL) at 72, 84, and 96 months after LSG was 52%, 43%, and 46%, respectively, with an overall EWL of 48%. The mean BMI decreased from 66 kg/m(2) (43-90) to 46 kg/m(2) (22-73). Seventy-seven percent of the diabetic patients showed improvement or remission of the disease.

CONCLUSIONS

This study reports the longest follow-up of LSG patients thus far and supports the effectiveness, safety, and durability of laparoscopic sleeve gastrectomy as a definitive therapeutic option for severe obesity, even in high-risk, high-BMI patients.

摘要

目的

本研究报告了接受腹腔镜袖状胃切除术(LSG)的高危、高体重指数(BMI)患者的长期结果。

背景

短期和中期数据似乎支持 LSG 的有效性,但支持其耐久性的长期数据很少。

方法

对 2002 年 1 月至 2004 年 2 月期间作为严重肥胖手术治疗分阶段方法一部分接受 LSG 的所有高危患者进行前瞻性数据库回顾。我们仅纳入未进行第二阶段手术(胃旁路术)的患者。分析数据包括人口统计学资料、BMI、合并症和手术结果。所有部分胃切除术均使用 50F 探条进行。

结果

74 例患者接受了 LSG,74 例患者中有 69 例(93%)获得了随访数据。平均年龄为 50 岁(25-78 岁),平均合并症数为 9.6 个。围手术期死亡率(<30 天)为零,短期和长期术后并发症发生率为 15%。平均总随访时间为 73 个月(38-95)。LSG 后 72、84 和 96 个月的平均超重减轻(EWL)分别为 52%、43%和 46%,总体 EWL 为 48%。平均 BMI 从 66kg/m²(43-90)降至 46kg/m²(22-73)。77%的糖尿病患者病情改善或缓解。

结论

本研究报告了迄今为止 LSG 患者最长的随访结果,支持腹腔镜袖状胃切除术作为严重肥胖症的一种确定性治疗选择的有效性、安全性和耐久性,即使在高危、高 BMI 患者中也是如此。

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