Departamento de Bioquímica, Genética e Inmunología, Facultad de Biología, Universidad de Vigo, Vigo, Pontevedra, Spain.
Heredity (Edinb). 2011 May;106(5):765-74. doi: 10.1038/hdy.2010.117. Epub 2010 Sep 8.
A dynamic method (DM) recently proposed for the management of captive subdivided populations was evaluated using the pilot species Drosophila melanogaster. By accounting for the particular genetic population structure, the DM determines the optimal mating pairs, their contributions to progeny and the migration pattern that minimize the overall co-ancestry in the population with a control of inbreeding levels. After a pre-management period such that one of the four subpopulations had higher inbreeding and differentiation than the others, three management methods were compared for 10 generations over three replicates: (1) isolated subpopulations (IS), (2) one-migrant-per-generation rule (OMPG), (3) DM aimed to produce the same or lower inbreeding coefficient than OMPG. The DM produced the lowest co-ancestry and equal or lower inbreeding than the OMPG method throughout the experiment. The initially lower fitness and lower variation for nine microsatellite loci of the highly inbred subpopulation were restored more quickly with the DM than with the OMPG method. We provide, therefore, an empirical illustration of the usefulness of the DM as a conservation protocol for captive subdivided populations when pedigree information is available (or can be deduced) and manipulation of breeding pairs is possible.
最近提出的一种用于管理圈养细分种群的动态方法（DM），使用模式生物黑腹果蝇进行了评估。通过考虑特定的遗传种群结构，DM 确定了最佳交配对、它们对后代的贡献以及最小化种群整体共同祖先的迁移模式，同时控制近亲繁殖水平。在预先管理期后，四个亚种群中的一个比其他亚种群具有更高的近亲繁殖和分化，在三个重复实验中比较了三种管理方法 10 代：（1） 隔离亚种群（IS），（2） 每代一代移民规则（OMPG），（3） DM 旨在产生与 OMPG 相同或更低的近交系数。在整个实验过程中，DM 产生的共同祖先和近交系数都低于或等于 OMPG 方法。最初高度近亲繁殖的亚种群的九个微卫星基因座的适应性和变异较低，与 OMPG 方法相比，DM 能更快地恢复其适应性和变异。因此，当有谱系信息（或可以推断出）并且可以操纵繁殖对时，我们提供了 DM 作为圈养细分种群保护协议的有用性的实证例证。
