Suppr超能文献

为接受美沙酮维持治疗的退伍军人提供现场基本健康筛查及慢性疾病简要健康咨询

On-site Basic Health Screening and Brief Health Counseling of Chronic Medical Conditions for Veterans in Methadone Maintenance Treatment.

作者信息

Fareed Ayman, Musselman Dominique, Byrd-Sellers Johnita, Vayalapalli Sreedevi, Casarella Jennifer, Drexler Karen, Phillips Lawrence

机构信息

Atlanta Veterans Administration Medical Center, Decatur, Georgia.

出版信息

J Addict Med. 2010 Sep;4(3):160-166. doi: 10.1097/ADM.0b013e3181b6f4e5.

Abstract

BACKGROUND

In order to improve the delivery of health services for chronic medical conditions in our methadone clinic, we added an onsite health screening and brief health counseling to the treatment plans for patients receiving methadone maintenance treatment at the Atlanta Veterans Affairs Medical Center (VAMC). We then conducted a follow up retrospective chart review to assess whether this intervention improved health outcome for those patients. METHODS: We reviewed the charts of one hundred and two patients who received treatment at Atlanta VAMC methadone clinic between 2002 and 2008. We sought to determine whether our increased health education and screening intervention was associated with improved: 1) Improved drug addiction outcome (as measured by comparing percentage of opiate and cocaine positive drug screens from admission to most recent). 2) Basic health screening, (as measured by the patient's compliance with primary care physicians (PCP) appointments and current smoking status). 3) Management of co-occurring medical conditions (as measured by levels of LDL cholesterol, hemoglobin A1c, and systolic blood pressure (SBP). 4) Presence of QTc prolongation (difference in QTc between baseline and most recent EKG). RESULTS: Illicit drug use (opiate and cocaine) markedly decreased in patients overall. The effect was more robust for those successfully "retained" (n=55, p<0.0001) in treatment, compared to those who "dropped out" (n=40, p=0.05) of treatment. Compliance with PCP appointments was high (82% and 88% before and after the onsite intervention, respectively) for "retained" patients. LDL cholesterol level was within normal range for all patients. A1c improved by 40% after the onsite intervention as reflected by the decreased percentage of patients with A1c > 7 % from before to after the intervention (90% vs. 50%, p=0.05). However, the prevalence of uncontrolled hypertension did not significantly improve after the onsite intervention (38% vs. 28%, p=0.34). As might be expected with MMT, the prevalence of QTc prolongation actually increased from 399 m sec. (+/- 92) to 439 msec. (+/- 22) after the onsite intervention (p=0.003). CONCLUSIONS: Our retrospective study supports the previous literature that methadone maintenance therapy is effective in reducing illicit drug use. Although patients with history of heroin dependence and in methadone maintenance treatment are at increased risk for chronic medical conditions like hepatitis C and diabetes, there are minimal federal guidelines for medical care, except than a physical exam upon admission, and basic screening for some infectious diseases e.g. HIV and Hepatitis C for those patients. Our study demonstrated the need for and potential benefit of enhancing the delivery of health promotion services for chronic medical conditions in methadone maintained patients. Improving management of hepatitis C, diabetes, hypertension, and other related conditions, in this high risk, difficult-to-treat, and underserved population may reduce their morbidity and premature mortality.

摘要

背景

为改善我们美沙酮诊所慢性疾病的医疗服务,我们在亚特兰大退伍军人事务医疗中心(VAMC)接受美沙酮维持治疗的患者治疗计划中增加了现场健康筛查和简短健康咨询。然后,我们进行了一项后续回顾性病历审查,以评估该干预措施是否改善了这些患者的健康结局。方法:我们审查了2002年至2008年期间在亚特兰大VAMC美沙酮诊所接受治疗的102名患者的病历。我们试图确定增加的健康教育和筛查干预措施是否与以下方面的改善相关:1)改善药物成瘾结局(通过比较入院时与最近一次鸦片和可卡因阳性药物筛查的百分比来衡量)。2)基本健康筛查(通过患者对初级保健医生(PCP)预约的依从性和当前吸烟状况来衡量)。3)并发疾病的管理(通过低密度脂蛋白胆固醇、糖化血红蛋白A1c和收缩压(SBP)水平来衡量)。4)QTc延长的存在(基线与最近一次心电图之间QTc的差异)。结果:总体而言,患者的非法药物使用(鸦片和可卡因)明显减少。与“退出”治疗的患者(n = 40,p = 0.05)相比,成功“维持”治疗的患者(n = 55,p < 0.0001)效果更显著。“维持”治疗的患者对PCP预约的依从性很高(现场干预前后分别为82%和88%)。所有患者的低密度脂蛋白胆固醇水平均在正常范围内。现场干预后,A1c改善了40%,这反映在干预前后A1c > 7%的患者百分比下降(90%对50%,p = 0.05)。然而,现场干预后未控制高血压的患病率没有显著改善(38%对28%,p = 0.34)。正如美沙酮维持治疗可能预期的那样,现场干预后QTc延长的患病率实际上从399毫秒(±92)增加到439毫秒(±22)(p = 0.003)。结论:我们的回顾性研究支持先前的文献,即美沙酮维持治疗在减少非法药物使用方面是有效的。尽管有海洛因依赖史且接受美沙酮维持治疗的患者患丙型肝炎和糖尿病等慢性疾病的风险增加,但除入院时的体格检查以及对这些患者进行一些传染病(如HIV和丙型肝炎)的基本筛查外,联邦医疗指南很少。我们的研究表明,有必要为接受美沙酮维持治疗的患者加强慢性疾病健康促进服务的提供,并证明了这样做的潜在益处。在这个高风险、难以治疗且服务不足的人群中,改善丙型肝炎、糖尿病、高血压和其他相关疾病的管理可能会降低他们的发病率和过早死亡率。

相似文献

7
QTc Prolongation in Veterans With Heroin Dependence on Methadone Maintenance Treatment.接受美沙酮维持治疗的海洛因依赖退伍军人的QTc间期延长
Int J High Risk Behav Addict. 2015 Jun 20;4(2):e23819. doi: 10.5812/ijhrba.4(2)2015.23819. eCollection 2015 Jun.

引用本文的文献

本文引用的文献

2
QTc interval screening in methadone treatment.美沙酮治疗中的QTc间期筛查
Ann Intern Med. 2009 Mar 17;150(6):387-95. doi: 10.7326/0003-4819-150-6-200903170-00103. Epub 2009 Jan 19.
5
Viral hepatocarcinogenesis: from infection to cancer.病毒性肝癌发生:从感染到癌症
Liver Int. 2008 Feb;28(2):175-88. doi: 10.1111/j.1478-3231.2007.01652.x.
10
Disorders of glucose metabolism among HIV-infected women.感染艾滋病毒女性的葡萄糖代谢紊乱
Clin Infect Dis. 2005 May 15;40(10):1492-9. doi: 10.1086/429824. Epub 2005 Apr 11.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验