Heratizadeh A, Völker B, Kupsch E, Wichmann K, Kapp A, Werfel T
Klinik für Dermatologie, Allergologie und Venerologie, Medizinische Hochschule Hannover, Ricklinger Str. 5, 30449, Hannover.
Hautarzt. 2010 Dec;61(12):1052-5. doi: 10.1007/s00105-010-1998-4.
A 19-year-old patient presented with epidermodysplasia verruciformis (EV). In this genodermatosis, pathogenetic factors such as infection by human papilloma viruses as well as sun exposure are considered responsible for the malignant transformation of EV lesions to skin cancer within decades. So far, several therapeutic strategies have been unsatisfactory. In our case HPV 5b was detected and the associated skin lesions were successfully treated with imiquimod 5% cream.
一名19岁的患者被诊断为疣状表皮发育不良(EV)。在这种遗传性皮肤病中,人乳头瘤病毒感染以及阳光照射等致病因素被认为是导致EV病变在数十年内恶变为皮肤癌的原因。到目前为止,几种治疗策略都不尽人意。在我们的病例中检测到了HPV 5b,相关的皮肤病变用5%咪喹莫特乳膏成功治疗。