鼻颅底手术后的鼻部不适：一项前瞻性队列研究。
Nasal morbidity following endoscopic skull base surgery: a prospective cohort study.
机构信息
Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
出版信息
Head Neck. 2011 Apr;33(4):547-51. doi: 10.1002/hed.21483. Epub 2010 Sep 7.
BACKGROUND
Nasal morbidity following skull base surgery necessitates follow-up for postoperative care. We describe nasal morbidity following endoscopic skull base surgery.
METHODS
Patient and operative data and postoperative subjective and objective measures of morbidity were prospectively collected for 1 year. Time to absence of crusting and remucosalization were determined. Risk factor analyses for crusting and nasal discharge were performed.
RESULTS
Nasal crusting (98%) and discharge (46%) were the most common postoperative symptoms. Median time to absence of crusting was 101.0 days, with longer times for complex cases (p = .033) but not for patients with septal flaps or fat grafts. Median time to remucosalization after nasoseptal flap was 89.0 days. There were no risk factors for crusting, although surgical complexity was a risk factor for postoperative discharge (odds ratio [OR] = 5.17).
CONCLUSIONS
Nasal morbidity following endoscopic skull base surgery is common and may be affected by surgical complexity and use of the nasoseptal flap.
背景
颅底手术后的鼻部不适需要进行术后护理。我们描述了内镜颅底手术后的鼻部不适。
方法
前瞻性收集了 1 年的患者和手术数据以及术后主观和客观的发病率测量指标。确定无结痂和再上皮化的时间。对结痂和鼻分泌物的风险因素进行了分析。
结果
最常见的术后症状是鼻腔结痂（98%）和分泌物（46%）。无结痂的中位时间为 101.0 天，复杂病例的时间更长（p =.033），但与使用鼻中隔瓣或脂肪移植物无关。鼻中隔瓣后再上皮化的中位时间为 89.0 天。虽然手术复杂性是术后分泌物的一个危险因素（比值比[OR] = 5.17），但没有结痂的危险因素。
结论
内镜颅底手术后的鼻部不适很常见，可能与手术复杂性和使用鼻中隔瓣有关。
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