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多个候选基因中单核苷酸多态性与商业安格斯杂交群体胴体和肉质性状的关联。

Associations between single nucleotide polymorphisms in multiple candidate genes and carcass and meat quality traits in a commercial Angus-cross population.

机构信息

The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Roslin BioCentre, Roslin, Midlothian EH25 9PS, UK.

出版信息

Meat Sci. 2010 Dec;86(4):985-93. doi: 10.1016/j.meatsci.2010.08.005. Epub 2010 Aug 17.

Abstract

The aim of this study was to evaluate the effects of 28 single nucleotide polymorphisms (SNP) in 10 candidate genes previously shown to be associated with quality traits in pigs and cattle. The data set comprised 28 traits recorded on a commercial population of 536 Aberdeen Angus-cross beef cattle. Among the traits, 20 were carcass and sirloin quality related, one mechanical measure of tenderness, and the remaining seven were taste panel assessed sensory traits. The candidate genes studied included growth hormone (GH) and pro-opiomelanocortin (POMC). Association analysis showed that 13 of the 28 SNPs were significantly associated with at least one of the traits. Some of these were novel (POMC and mechanical tenderness), whilst others confirmed previous results (GH and eye muscle length). Following validation in other populations and breeds, these markers could be incorporated into breeding programs to increase the rate of improvement in carcass and meat quality traits.

摘要

本研究旨在评估 10 个候选基因中 28 个单核苷酸多态性(SNP)的影响,这些基因先前与猪和牛的肉质性状有关。数据集包括在一个商业的 536 头安格斯牛杂交肉牛群体中记录的 28 个性状。其中 20 个与胴体和里脊品质有关,1 个与嫩度的机械测量有关,其余 7 个是品尝小组评估的感官性状。研究的候选基因包括生长激素(GH)和促肾上腺皮质激素原(POMC)。关联分析显示,28 个 SNP 中有 13 个与至少一个性状显著相关。其中一些是新的(POMC 和机械嫩度),而另一些则证实了先前的结果(GH 和眼肌长度)。在其他群体和品种中得到验证后,这些标记物可以被纳入到育种计划中,以提高胴体和肉质性状的改良速度。

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