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奶牛育种技术的创新:基因编辑时代的前景

Innovations in Cattle Breeding Technology: Prospects in the Era of Gene Editing.

作者信息

Wang Yu, Cui Xiangshun, Chen Zhi

机构信息

College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.

Laboratory of Animal Developmental Biology, Department of Animal Science, Chungbuk National University, Cheongju 28644, Republic of Korea.

出版信息

Animals (Basel). 2025 May 8;15(10):1364. doi: 10.3390/ani15101364.

Abstract

As a core species in the global livestock industry, cattle play an irreplaceable role in human food security and economic development. Beef cattle and dairy cattle meet the dietary needs of billions of people around the world by providing high-quality protein and dairy products, respectively. With the growth in population and the intensification of the pressure of climate change, traditional breeding techniques may be unsuitable to meet the increasingly growing demands for sustainable and highly adaptable processes. In recent years, the rapid development of genomics, bioinformatics, and gene-editing technologies has provided unprecedented tools and perspectives for the genetic improvement of cattle, driving the precise design and efficient development of new cattle breeds. However, the development of new cattle breeds still faces multiple bottlenecks pertaining to scientific, ethical, and industrialization aspects, which can be addressed through interdisciplinary collaboration. In this review, we will systematically assess the technological progress in the genetic breeding of beef cattle and dairy cattle, analyze the integration path of traditional breeding and modern biotechnology, and explore the future directions of cattle breeding research under the sustainable development goals, with the aim of providing theoretical support for cattle breeding.

摘要

作为全球畜牧业的核心物种,牛在人类粮食安全和经济发展中发挥着不可替代的作用。肉牛和奶牛分别通过提供高质量蛋白质和乳制品,满足了全球数十亿人的饮食需求。随着人口增长和气候变化压力的加剧,传统育种技术可能无法满足对可持续且高度适应性过程日益增长的需求。近年来,基因组学、生物信息学和基因编辑技术的快速发展为牛的遗传改良提供了前所未有的工具和视角,推动了新型牛品种的精确设计和高效培育。然而,新型牛品种的培育仍面临科学、伦理和产业化等多方面的瓶颈,可通过跨学科合作加以解决。在本综述中,我们将系统评估肉牛和奶牛遗传育种的技术进展,分析传统育种与现代生物技术的融合路径,并探索可持续发展目标下牛育种研究的未来方向,旨在为牛育种提供理论支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9e9/12108293/8e8300d3ba43/animals-15-01364-g001.jpg

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