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脱水对生物软组织力学行为的影响:肾脏组织的观察。

Dehydration effect on the mechanical behaviour of biological soft tissues: observations on kidney tissues.

机构信息

Université de Lyon, F-69622, Lyon, France.

出版信息

J Mech Behav Biomed Mater. 2010 Nov;3(8):630-5. doi: 10.1016/j.jmbbm.2010.07.010. Epub 2010 Jul 27.

Abstract

This paper deals with the effects of dehydration on the mechanical properties of biological soft tissues and with the validity of methods used in previous works such as a coat of petroleum jelly or silicon oil to minimise the drying of the tissue during mechanical testing. We find that the samples get stiffer as they dry but that this phenomenon is wholly reversible upon re-hydrating the samples. A bath of saline solution is the best hydration method but a coat of low-viscosity silicon oil around the free edge of the sample also proves to be a good anti-drying method. However, using petroleum jelly to prevent tissue dehydration should be banned because the jelly largely contributes to the measured mechanical moduli.

摘要

本文研究了脱水对生物软组织力学性能的影响,并探讨了先前研究中使用的一些方法的有效性,例如在机械测试过程中使用凡士林或硅油涂层来尽量减少组织干燥。我们发现,随着组织干燥,样本变得越来越硬,但在重新水合样本后,这种现象是完全可逆的。生理盐水浴是最好的水合方法,但在样本自由边缘涂一层低粘度硅油也被证明是一种很好的防干燥方法。然而,应该禁止使用凡士林来防止组织脱水,因为凡士林会极大地影响测量的力学模量。

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