Dana-Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02115, USA.
Cancer Epidemiol Biomarkers Prev. 2010 Sep;19(9):2187-98. doi: 10.1158/1055-9965.EPI-10-0217.
Prophylactic human papillomavirus (HPV) vaccines are available, but uptake is suboptimal. Information on factors influencing parental decisions regarding vaccination will facilitate the development of successful interventions.
Parents of girls ages 9 to 17 years (n = 476; cooperation rate = 67%) from a panel of U.S. households completed online surveys between September 2007 and January 2008, documenting vaccine knowledge, attitudes, and intentions.
Among those aware of the vaccine, 19% had already vaccinated their daughter(s), 34% intended to, 24% were undecided, and 24% had decided against vaccination. Awareness of HPV was high but knowledge levels were suboptimal (mean 72%, SEM 0.8%). Black and Hispanic parents were significantly less likely to be aware of the vaccine compared with White parents. In multivariate analyses, compared with parents who opposed vaccination, those who had already vaccinated their daughter(s) or who intended to do so had more positive attitudes, reported fewer barriers, and were more likely to perceive that family and friends would endorse vaccination. They also reported higher levels of trust in pharmaceutical companies that produce the vaccine.
Despite limited knowledge, most parents had decided to vaccinate their daughter(s). Given evidence of diminished access to information among Black and Hispanic parents, programs should focus on reaching these groups. Interventions should address parental concerns about behavioral consequences, reduce structural barriers, and promote the perception that vaccination is endorsed by significant others. Moreover, interventions may need to address mistrust of pharmaceutical companies. IMPACT STATEMENT: This study documents factors associated with parental decisions about HPV vaccination for their daughter(s) and provides direction for intervention development.
预防性人乳头瘤病毒(HPV)疫苗已经问世,但接种率并不理想。了解影响父母对疫苗接种决策的因素,将有助于制定成功的干预措施。
来自美国家庭小组的 476 名 9 至 17 岁女孩的父母(合作率=67%)在 2007 年 9 月至 2008 年 1 月期间完成了在线调查,记录了疫苗知识、态度和接种意向。
在了解疫苗的人群中,19%已经为女儿接种了疫苗,34%打算接种,24%尚未决定,24%决定不接种。对 HPV 的认识度较高,但知识水平不理想(平均 72%,SEM 0.8%)。与白人父母相比,黑人和西班牙裔父母明显不太了解疫苗。在多变量分析中,与反对接种疫苗的父母相比,已经为女儿接种疫苗或打算接种疫苗的父母态度更为积极,报告的障碍较少,更倾向于认为家人和朋友会支持接种疫苗。他们也报告对生产疫苗的制药公司的信任度更高。
尽管知识有限,但大多数父母已经决定为女儿接种疫苗。鉴于黑人和西班牙裔父母获取信息的机会有限,应针对这些群体开展项目。干预措施应解决父母对行为后果的担忧,减少结构性障碍,并增强他人对疫苗接种的支持感。此外,干预措施可能需要解决对制药公司的不信任。
本研究记录了与父母对女儿 HPV 疫苗接种决策相关的因素,并为干预措施的制定提供了方向。