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使用放射变色薄膜测量冠状动脉介入手术期间的患者皮肤剂量

Patient skin dose measurements during coronary interventional procedures using Gafchromic film.

作者信息

Ying C K, Kandaiya S

机构信息

School of Physics, Universiti Sains Malaysia (USM), Penang, Malaysia.

出版信息

J Radiol Prot. 2010 Sep;30(3):585-96. doi: 10.1088/0952-4746/30/3/012. Epub 2010 Sep 8.

DOI:10.1088/0952-4746/30/3/012
PMID:20826892
Abstract

Interventional cardiology (IC) procedures are known to give high radiation doses to patients and cardiologists as they involve long fluoroscopy times and several cine runs. Patients' dose measurements were carried out at the cardiology department in a local hospital in Penang, Malaysia, using Gafchromic XR-RV2 films. The dosimetric properties of the Gafchromic film were first characterised. The film was energy and dose rate independent but dose dependent for the clinically used values. The film had reproducibility within ± 3% when irradiated on three different days and hence the same XR-RV2 dose-response calibration curve can be used to obtain patient entrance skin dose on different days. The increase in the response of the film post-irradiation was less than 4% over a period of 35 days. For patient dose measurements, the films were placed on the table underneath the patient for an under-couch tube position. This study included a total of 44 patients. Values of 35-2442 mGy for peak skin dose (PSD) and 10.9-344.4 Gy cm(2) for dose-area product (DAP) were obtained. DAP was found to be a poor indicator of PSD for PTCA procedures but there was a better correlation (R(2) = 0.7344) for CA + PTCA procedures. The highest PSD value in this study exceeded the threshold dose value of 2 Gy for early transient skin injury recommended by the Food and Drug Administration.

摘要

介入心脏病学(IC)手术因涉及较长的透视时间和多次电影摄影运行,已知会给患者和心脏病专家带来高辐射剂量。在马来西亚槟城的一家当地医院的心脏病科,使用Gafchromic XR-RV2胶片对患者进行了剂量测量。首先对Gafchromic胶片的剂量学特性进行了表征。该胶片在临床使用值范围内与能量和剂量率无关,但与剂量有关。当在三天不同时间进行照射时,该胶片的再现性在±3%以内,因此可以使用相同的XR-RV2剂量-响应校准曲线在不同日期获取患者的入射皮肤剂量。在35天的时间内,照射后胶片响应的增加小于4%。对于患者剂量测量,将胶片放置在患者下方的检查台上,采用床下管位置。本研究共纳入44例患者。获得的峰值皮肤剂量(PSD)值为35 - 2442 mGy,剂量面积乘积(DAP)值为10.9 - 344.4 Gy cm²。对于经皮冠状动脉腔内血管成形术(PTCA)手术,发现DAP是PSD的一个较差指标,但对于冠状动脉造影(CA)+PTCA手术,两者有更好的相关性(R² = 0.7344)。本研究中最高的PSD值超过了美国食品药品监督管理局推荐的早期短暂性皮肤损伤的2 Gy阈值剂量值。

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