Somosy Z, Kubasova T, Csuka O, Köteles G J
Frédéric Joliot-Curie, National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary.
Acta Physiol Hung. 1990;76(2):143-9.
The amount and distribution of negatively charged sites of different cells (human fibroblasts, B16 melanoma cells, a human lymphoid leukemic cell type) were investigated. In the non-irradiated fibroblasts and B16 melanoma cells the negatively charged sites were localized mainly on apical and lateral surfaces as well as in a polarized manner. However, negatively charged sites on the control human lymphoid leukemic cells often have patched distribution. It was demonstrated that the amount and distribution of negatively charged sites on primary human fibroblasts and B16 melanoma cells changed upon ionizing radiation. However, the topology of negative charges on investigated human leukemic cell membrane did not change.
研究了不同细胞（人成纤维细胞、B16黑色素瘤细胞、一种人淋巴白血病细胞类型）带负电位点的数量和分布。在未受辐照的成纤维细胞和B16黑色素瘤细胞中，带负电位点主要定位于顶端和侧面表面，且呈极化分布。然而，对照人淋巴白血病细胞上的带负电位点常常呈斑块状分布。结果表明，人原代成纤维细胞和B16黑色素瘤细胞上带负电位点的数量和分布在电离辐射后发生了变化。然而，所研究的人白血病细胞膜上负电荷的拓扑结构并未改变。
