二甲双胍对去势雌性大鼠生殖系统的影响。
Effects of metformin on the reproductive system of androgenized female rats.
机构信息
Gynecology Department, Federal University of São Paulo, São Paulo, Brazil.
出版信息
Fertil Steril. 2011 Mar 15;95(4):1507-9. doi: 10.1016/j.fertnstert.2010.07.1093. Epub 2010 Sep 9.
Abstract
Metformin improved the glucose rate and the homeostasis model assessment-insulin resistance (HOMA-IR) index and caused partial reversion of ovaries and uterine morphology in female rats androgenized with testosterone.
摘要
二甲双胍改善了葡萄糖水平和稳态模型评估-胰岛素抵抗（HOMA-IR）指数，并使雄激素化大鼠的卵巢和子宫形态部分恢复正常。
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