Division of Urogynecology and Reconstructive Pelvic Surgery, Carmel Medical Center, Technion University Rappaport Faculty of Medicine, Haifa, Israel.
Fertil Steril. 2011 Mar 15;95(4):1467-70. doi: 10.1016/j.fertnstert.2010.08.001. Epub 2010 Sep 9.
We aimed to assess the effect of bilateral oophorectomy on vaginal wound healing in three groups of New Zealand White rabbits (24 rabbits each). Group 1 underwent bilateral oophorectomy, group 2 underwent a sham surgery, and group 3 served as control. Standardized vaginal tissue specimens were harvested and assessed for wound and scar surface area and tensiometric analysis before wounding, and sequentially thereafter, showing that vaginal wound closure, scar contraction, and recovery of biomechanical properties are significantly slower in oophorectomized rabbits.
我们旨在评估三组新西兰白兔（每组 24 只）双侧卵巢切除术对阴道伤口愈合的影响。第 1 组行双侧卵巢切除术，第 2 组行假手术，第 3 组作为对照。在受伤前、受伤后依次采集标准化阴道组织标本，评估伤口和疤痕表面积，并进行张力分析，结果显示卵巢切除兔的阴道伤口闭合、疤痕收缩和生物力学特性恢复明显较慢。
