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老年人的焦虑和抑郁:我们了解更多了吗?

Anxiety and depression in the elderly: do we know any more?

机构信息

School of Medicine, University of Queensland, Mental Health Service, Royal Brisbane & Women's Hospital, Brisbane, Queensland, Australia.

出版信息

Curr Opin Psychiatry. 2010 Nov;23(6):504-9. doi: 10.1097/YCO.0b013e32833f305f.

Abstract

PURPOSE OF REVIEW

The advent of global population ageing raises understandable concerns about the high-prevalence mental disorders in older people. Accordingly, this review covers recently published scientific articles concerning anxiety and depression.

RECENT FINDINGS

There is a paucity of findings on anxiety in older people, although the availability of several new scales suggests increased interest in this topic. The low prevalence of late-life depression in many population surveys does not appear to be due to misattribution of depressive symptoms to physical disorders. Although it is well established that dementia leads to depression, there is now increasing evidence for the proposition that depression leads to cognitive decline and dementia. There is now good evidence also for a bidirectional relationship between obesity and depression. The prognosis of treated late-life depression varies with baseline neuropsychological function and the severity of white matter hyperintensities.

SUMMARY

An excellent body of research on depression in older people is now available, although more work on both pharmacological and nonpharmacological treatments is needed. More research is urgently required into anxiety disorders in older people. These are highly prevalent and associated with considerable disease burden. As the literature on depression in older people reaches maturity, there should be greater research and clinical interest in anxiety.

摘要

目的综述

全球人口老龄化的出现引发了人们对老年人高发精神障碍的合理担忧。因此,本综述涵盖了最近发表的关于焦虑和抑郁的科学文章。

最近的发现

关于老年人焦虑的研究结果很少,尽管有几个新的量表出现,表明人们对这个话题的兴趣有所增加。许多人群调查中,晚年抑郁症的低患病率似乎并不是由于将抑郁症状归因于身体疾病所致。尽管痴呆症会导致抑郁已经得到充分证实,但越来越多的证据表明抑郁会导致认知能力下降和痴呆症。现在也有充分的证据表明肥胖和抑郁之间存在双向关系。经过治疗的晚年抑郁症的预后因基线神经心理学功能和白质高信号的严重程度而异。

总结

现在已经有大量关于老年人抑郁症的研究,尽管还需要更多关于药物和非药物治疗的研究。需要紧急研究老年人的焦虑障碍。这些疾病发病率高,疾病负担大。随着关于老年人抑郁症的文献逐渐成熟,应该有更多的研究和临床关注焦虑症。

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