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[慢性依那普利治疗对原发性高血压患者月经周期中肾素原、肾素和性激素的影响]

[Effect of chronic enalapril treatment on prorenin, renin and sex hormones during the menstrual cycle in patients with essential hypertension].

作者信息

Troffa C, Tonolo G, Manunta P, Pinna Parpaglia P, Madeddu P, Melis M G, Soro A, Pala F, Pazzola A, Patteri G

机构信息

Centro Ipertensione, Clinica Medica, Università di Sassari.

出版信息

Boll Soc Ital Biol Sper. 1990 Jul;66(7):663-70.

PMID:2083060
Abstract

Since angiotensin II seems to be involved in the process of ovulation we studied the effect of chronic enalapril on plasma prorenin, renin, estradiol, progesterone, LH and FSH during the menstrual cycle in ten essential hypertensive women. Our data show that peripheral blockade of A I conversion does not affect the pituitary guidance and the ovarian hormonal response of the menstrual cycle and, we can speculate, that it does not interfere with the process of ovulation.

摘要

由于血管紧张素II似乎参与排卵过程,我们研究了慢性服用依那普利对10名原发性高血压女性月经周期中血浆血管紧张素原、肾素、雌二醇、孕酮、促黄体生成素和促卵泡生成素的影响。我们的数据表明,血管紧张素I转化的外周阻断不会影响月经周期的垂体调控和卵巢激素反应,并且我们可以推测,它不会干扰排卵过程。

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