Pacific Health Research Institute, Honolulu, HI, United States.
Prim Care Diabetes. 2010 Dec;4(4):215-22. doi: 10.1016/j.pcd.2010.07.002. Epub 2010 Sep 15.
The broad objective of this study was to examine multiple dimensions of depression in a large, diverse population of adults with diabetes. Specific aims were to measure the association of depression with: (1) patient characteristics; (2) outcomes; and (3) diabetes-related quality of care.
Cross-sectional analyses were performed using survey and chart data from the Translating Research Into Action for Diabetes (TRIAD) study, including 8790 adults with diabetes, enrolled in 10 managed care health plans in 7 states. Depression was measured using the Patient Health Questionnaire (PHQ-8). Patient characteristics, outcomes and quality of care were measured using validated survey items and chart data.
Nearly 18% of patients had major depression, with prevalence 2-3 times higher among patients with low socioeconomic status. Pain and limited mobility were strongly associated with depression, controlling for other patient characteristics. Depression was associated with slightly worse glycemic control, but not other intermediate clinical outcomes. Depressed patients received slightly fewer recommended diabetes-related processes of care.
In a large, diverse cohort of patients with diabetes, depression was most prevalent among patients with low socioeconomic status and those with pain, and was associated with slightly worse glycemic control and quality of care.
本研究的总体目标是在患有糖尿病的大量多样化的成年人中,考察抑郁的多个维度。具体目的是衡量抑郁与以下方面的关联:(1)患者特征;(2)结局;以及(3)与糖尿病相关的护理质量。
使用来自 Translating Research Into Action for Diabetes(TRIAD)研究的调查和图表数据进行横断面分析,包括来自 7 个州的 10 个管理式医疗保健计划的 8790 名成年糖尿病患者。使用患者健康问卷(PHQ-8)衡量抑郁。使用经过验证的调查项目和图表数据衡量患者特征、结局和护理质量。
近 18%的患者患有重度抑郁症,社会经济地位较低的患者的患病率高出 2-3 倍。疼痛和行动能力受限与抑郁密切相关,控制了其他患者特征。抑郁与血糖控制略有恶化相关,但与其他中间临床结局无关。抑郁患者接受的一些建议的糖尿病相关护理过程较少。
在患有糖尿病的大量多样化患者队列中,社会经济地位较低的患者和有疼痛的患者中抑郁最为常见,与血糖控制略差和护理质量较差相关。