Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.
Best Pract Res Clin Gastroenterol. 2010 Aug;24(4):465-78. doi: 10.1016/j.bpg.2010.06.001.
Cancer is a leading cause of death worldwide and the burden could be reduced by evidence-based strategies for the primary prevention of cancer, the early detection of malignancies and more adequate treatment of cancer patients. Previous research has shown that lifestyle factors are associated with common cancers and that several cancer screening programmes are cost-effective in reducing cancer-specific mortality. But, some recent studies reported that participants of screening programs might unintentionally change their lifestyle. Cancer screening might be a teachable moment or, on the other hand, have a false health certificate effect. Despite that the evidence is scarce, cancer screening might have opportunities for lifestyle improvements, although a possible health certificate effect still remains. Integrated approaches to combine primary and secondary prevention have the potential to optimise the efforts to improve cancer prevention and survival. More research is warranted to investigate evidence-based approaches.
癌症是全球主要死因之一,通过循证策略可以减轻这一负担,这些策略包括癌症的一级预防、恶性肿瘤的早期发现和更充分的癌症患者治疗。先前的研究表明,生活方式因素与常见癌症有关,并且一些癌症筛查方案在降低癌症特异性死亡率方面具有成本效益。但是,一些最近的研究报告称,筛查计划的参与者可能会无意中改变他们的生活方式。癌症筛查可能是一个可教育的时刻,或者另一方面,具有虚假的健康证书效应。尽管证据有限,但癌症筛查可能有机会改善生活方式,尽管仍然存在可能的健康证书效应。综合应用一级和二级预防措施有可能优化改善癌症预防和生存的努力。需要进一步研究以调查基于证据的方法。