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结直肠癌筛查在不断扩展的筛查计划全景中。

Colorectal cancer screening in an expanding panorama of screening programmes.

机构信息

Cancer Registry of Norway, 5313 Majorstuen, 0304 Oslo, Norway.

出版信息

Best Pract Res Clin Gastroenterol. 2010 Aug;24(4):521-7. doi: 10.1016/j.bpg.2010.04.006.

Abstract

Cervical and breast cancer screening programmes have been introduced in times when both the professional requirements for evidence based medicine and public demand for quantification of benefits may have been less explicit. The World Health Organisation has recommended cancer screening only for cervix, breast and colorectal cancer (CRC) - the latter leaving health authorities with a choice between a multitude of screening methods of which the efficacy has been proven only for fecal occult blood testing (FOBT). Although we are far from seeing the perfect screening method and screening programme, cost effectiveness for CRC screening has been estimated at least as cost-effective as established programmes for cervix and breast cancer screening. Established and imminent screening programmes should be considered as natural platforms for randomised trial with commitment and responsibility to continuously improve the quality and effectiveness of the screening service provided.

摘要

宫颈癌和乳腺癌筛查项目是在当时提出的,当时循证医学的专业要求和公众对利益量化的需求可能还不那么明确。世界卫生组织仅推荐对宫颈癌、乳腺癌和结直肠癌(CRC)进行癌症筛查,这让卫生当局在多种已被证明有效的筛查方法中进行选择,其中只有粪便潜血检测(FOBT)被证明有效。尽管我们还远未看到完美的筛查方法和筛查项目,但 CRC 筛查的成本效益至少与已确立的宫颈癌和乳腺癌筛查项目一样具有成本效益。已建立和即将建立的筛查项目应被视为随机试验的自然平台,承诺并负责不断提高所提供的筛查服务的质量和效果。

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