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[大鼠实验中移植脑肿瘤血管系统的一些定量参数]

[Some quantitative parameters of the vascular system of transplanted brain tumors in experiments using rats].

作者信息

Levitman M Kh, Liubimova N V, Plotnikova E D, Shaposhnikova V V, Khalanskiĭ A S

出版信息

Biull Eksp Biol Med. 1990 Dec;110(12):638-41.

PMID:2083369
Abstract

A vascular system of several strains of brain tumors: neurinoma 46-1, gliomas: 11-9-2 and 101-8 were investigated by means of automatic analysis of microangiograms and histochemical-luminescent estimation of endothelial cells. It was shown that the mean quantity of vessels and their section-size in all strains of tumors are less than control independently of the rates of tumor development. The linear density of the endothelial cells appear less that in control vessels and is equal in different strains of tumors, though the inclination to hemorrhages in gliomas is higher than in neurinoma. The cause of this phenomenon is discussed.

摘要

通过对微血管造影进行自动分析以及对内皮细胞进行组织化学发光评估,对几种脑肿瘤菌株的血管系统进行了研究:神经鞘瘤46 - 1、胶质瘤:11 - 9 - 2和101 - 8。结果表明,所有肿瘤菌株中的血管平均数量及其截面大小均低于对照组,与肿瘤发展速度无关。内皮细胞的线性密度似乎低于对照血管,并且在不同肿瘤菌株中相等,尽管胶质瘤中出血倾向高于神经鞘瘤。讨论了这种现象的原因。

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