Bastiani F, Ayme S, Guys J M, Pelizzo G, Monfort G
Clinique Chirurgicale Infantile, CHU de la Timone-Enfants, Marseille.
Chir Pediatr. 1990;31(4-5):272-4.
The authors report a retrospective study of therapeutic abortions for antenatally diagnosed abnormalities, 146 fetuses are concerned during a five years period, an anatomo-pathological examination have been performed in all cases, malformations of central nervous system are the most frequent (62). 26 urologic abnormalities are especially detailed. There are 10 isolated urologic abnormalities, and 16 abnormalities multiples. All fetuses had renal lesions which could justified an intervention but the declaration at registration of congenital birth defects is not obligatory. A multidisciplinary approach to prenatal diagnosis and congenital birth must still developed for a better understanding.
作者报告了一项针对产前诊断异常进行治疗性流产的回顾性研究,在五年期间涉及146例胎儿,所有病例均进行了解剖病理学检查,中枢神经系统畸形最为常见(62例)。特别详细描述了26例泌尿系统异常。其中有10例孤立性泌尿系统异常,16例为多发性异常。所有胎儿都有肾脏病变,这可能成为进行干预的理由,但先天性出生缺陷登记声明并非强制性的。仍需发展一种多学科方法来进行产前诊断和先天性出生研究,以获得更好的理解。