Macharia W M, Mirza N M, Wafula E M, Onyango F E
Department of Paediatrics, University of Nairobi.
East Afr Med J. 1990 Dec;67(12):837-41.
Between January 1986 and July 1988, 356 children with bronchial asthma below 14 years of age were evaluated at the Kenyatta National Hospital. 21.3% experienced initial asthmatic attacks before the age of six months and 55.1% before 2 years. Only 8% of the study patients were below the age of 2 years at recruitment. The male:female ratio was 1:1. Physical exercise led to precipitation or worsening of attacks in 43.4% while 71.6% of the patients experienced attacks in the evening or at night. 18.5% and 42.9% had personal history of atopic dermatitis and allergic rhinitis respectively. The study shows that a substantial number of patients experience initial asthmatic attacks before the age of 6 months contrary to what has been previously believed.
1986年1月至1988年7月期间，肯尼亚国家医院对356名14岁以下的支气管哮喘儿童进行了评估。21.3%的儿童在6个月龄之前经历了首次哮喘发作，55.1%的儿童在2岁之前发作。在招募的研究患者中，只有8%的患者年龄在2岁以下。男女比例为1:1。43.4%的患者运动后会诱发或加重发作，而71.6%的患者在傍晚或夜间发作。分别有18.5%和42.9%的患者有特应性皮炎和过敏性鼻炎的个人病史。该研究表明，与之前的认知相反，相当多的患者在6个月龄之前经历了首次哮喘发作。
