Department of Chest Diseases, Baskent University School of Medicine, Ankara, Turkey.
Ann Thorac Med. 2010 Jul;5(3):171-3. doi: 10.4103/1817-1737.65043.
We describe an unusual case of lymphocytic pleural effusion associated with the use of cilazapril, a novel angiotensin-converting-enzyme inhibitor (ACEI). An 80-year-old male was prescribed cilazapril for hypertension. He subsequently presented with right chest pain and dry cough. He was found to have a lymphocytic pleural effusion on thoracentesis. Extensive workup, including open pleural biopsy, failed to reveal the etiology of the effusion. However, soon after the withdrawal of cilazapril, his clinical symptoms improved and the effusion disappeared. ACEI-induced pleural effusion has only been rarely reported. Drug-induced pleural effusion should be considered when formulating the differential diagnosis in a patient receiving ACEI.
我们描述了一例与使用新型血管紧张素转换酶抑制剂（ACEI）西拉普利相关的淋巴细胞性胸腔积液的不寻常病例。一名 80 岁男性因高血压被开处西拉普利。随后他出现右侧胸痛和干咳。胸腔穿刺发现淋巴细胞性胸腔积液。广泛的检查，包括开胸胸膜活检，未能揭示胸腔积液的病因。然而，在停用西拉普利后不久，他的临床症状改善，胸腔积液消失。ACEI 引起的胸腔积液很少有报道。当对接受 ACEI 治疗的患者进行鉴别诊断时，应考虑药物引起的胸腔积液。
