BODE 指数与 COPD 患者的生活质量相关吗？

Does the BODE index correlate with quality of life in patients with COPD?

机构信息

Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.

出版信息

J Bras Pneumol. 2010 Jul-Aug;36(4):447-52. doi: 10.1590/s1806-37132010000400009.

DOI:10.1590/s1806-37132010000400009

PMID:20835591

Abstract

OBJECTIVE

To determine whether the Body mass index, airway Obstruction, Dyspnea, and Exercise capacity (BODE) index correlates with health-related quality of life in patients with COPD.

METHODS

We evaluated 42 patients with COPD, quantifying the following: lung function parameters; anthropometric variables; exercise capacity, with the six-minute walk test; dyspnea, with the modified Medical Research Council (MRC) scale; the BODE index; and quality of life, with the modified Saint George's Respiratory Questionnaire (mSGRQ). Patients were divided into two groups by disease severity: FEV1 >or= 50% and FEV1 < 50%.

RESULTS

The mean BODE index was 2.58 ± 1.17 and 4.15 ± 1.81, respectively, for the FEV1 >or= 50% and FEV1 < 50% groups. There was a significant difference between the groups in terms of FEV1 and the FEV1/FVC ratio. There were moderate to significant correlations between the BODE index scores and all of the mSGRQ domains in the group of patients with FEV1 <50%.

CONCLUSIONS

The BODE index score correlated with the scores of all of the mSGRQ domains in COPD patients with FEV1 < 50%. Therefore, COPD patients with FEV1 < 50% die sooner and have a poorer quality of life.

摘要

目的

确定体重指数、气道阻塞、呼吸困难和运动能力（BODE）指数是否与 COPD 患者的健康相关生活质量相关。

方法

我们评估了 42 名 COPD 患者，量化了以下指标：肺功能参数；人体测量学变量；使用六分钟步行试验评估运动能力；使用改良版医学研究理事会呼吸困难量表（MRC）评估呼吸困难；BODE 指数；使用改良圣乔治呼吸问卷（mSGRQ）评估生活质量。根据 FEV1 值将患者分为两组：FEV1≥50%和 FEV1<50%。